816 Natural Sciences Complex Department of Chemistry University at Buffalo The State University of New York Buffalo, NY 14260-3000 Phone: (716)645-6800 ext. 2245 Fax: (716) 645-6963 Email: szypersk@buffalo.edu

• Prediploma Biochemistry, U Tübingen (D) 1984
• Prediploma Chemistry, TU Munich (D) 1985
• Diploma Chemistry, TU Munich (D) 1988
• Dr. sc. nat ETH, ETH Zürich (CH) 1992
• Habilitation, ETH Zürich (CH) 1998
• Visiting scientist, U Auckland (NZ) 1988
• Fellow of the Studienstiftung des Deutschen Volkes (1982-1988)
• Fellow im Verband der Chemischen Industrie (1989-1991)
• Medaille der ETH 1992
• Research Innovation Award 1999, Research Corporation
• Buck-Whitney Medal 2003 of the ACS
• Scientific American 50 Award 2003 for "Chemistry and Materials"
• Laukien Prize 2006
• 2007 SUNY Chancellor's Award for Excellence in Scholarship and Creative Activities

Structure determination of biological macromolecules using nuclear magnetic resonance (NMR) spectroscopy, Development of Bio-NMR techniques, Structural genomics, Investigation of cellular metabolism using carbon-13 NMR.

Our research focuses on:

1. Development of Bio-NMR methods for structural genomics. Our group participates in the Northeast Structural Genomics Consortium (NESC) and the New York Consortium on Membrane Protein Structure. High-throughput NMR structure determination is supported by the Center for Computational Research.
2. Structure determinations of biological macromolecules using nuclear magnetic resonance (NMR) spectroscopy.
3. Development of NMR-based structural biology in supercooled water.
4. Investigation of cellular metabolism in support of biotechnology research.
5. Metabonomics

• Primary User: Varian 750^a / 600^a spectrometers (^acoldprobe)
• Access to: Varian 600^b / 500^c / 500^d / 400 / 300 spectrometers (^bPROTASIS micro-flow probe, ^cnanoprobe, ^{d  1}H/¹⁸F/ ¹³C/ ¹⁵N/ ²H-probe)

Selected Recent Publications