- RNA folding
- Developing therapeutics that target RNA
- High throughput screening - Two Dimensional Combinatorial Screening
- Chemical Microarrays
- Genetic Disease
Matthew D. Disney
Assistant Professor
657 Natural Sciences Complex
Department of Chemistry
University at Buffalo
The State University of New York
Buffalo, NY 14260-3000
Phone: (716) 645-6800 ext. 2170
Fax: (716) 645-6963
E-mail: mddisney@buffalo.edu
- B. S. Chemistry, University of Maryland, College Park (1997)
- M. S. Chemistry, University of Rochester, Rochester, NY (1999)
- Ph.D. Biophysical Chemistry, University of Rochester, Rochester, NY (2002)
- Postdoctoral Fellow Organic Chemistry, Massachusetts Institute of Technology and Swiss Federal Institute of Technology, Zurich, Switzerland (2002-2005)
- Roche Foundation Postdoctoral Fellow (2003-2005)
The Disney Laboratory is generally interested in developing a chemical code to
enable the rational and modular design of small molecules targeting RNA. We use
this chemical code to target RNAs that are involved in diseases such as cancer,
and a host of inherited diseases, and bacterial and viral infections. We also
have interests in developing microarray technologies as general platforms in
drug discovery through using them to develop cell-specific ligands and
antibiotics that evade resistance.
Selected Recent Publications