Publications of Dr. Michael Detty

1. McKnight, R. E.; Ye, M.; Ohulchanskyy, T. Y.; Sahabi, S.; Wetzel, B. R.; Wagner, S. J.; Skripchenko, A.; Detty, M. R. “Synthesis of Analogues of a Flexible Thiopyrylium Photosensitizer for Purging Blood-Borne Pathogens and Binding Mode and Affinity Studies of Their Complexes with DNA,” Bioorg. Med. Chem. 2007, 15, 4406-4418.
2. Gannon, M. K., II; Detty, M. R. “Generation of 3- and 5-Lithiothiophene-2-carboxylates via Metal-Halogen Exchange and Their Addition Reactions to Chalcogenoxanthones,” J. Org. Chem. 2007, 72, 2647-2650.
3. Holt, J. J.; Calitree, B. D.; Vincek, J.; Gannon, M. K., II; Detty, M. R. “A Microwave-Assisted Synthesis of Julolidine-9-carboxamide Derivatives and Their Conversion to Chalcogenoxanthones via Directed Metalation,” J. Org. Chem. 2007, 72, 2690-2693.
4. You, Y.; Daniels, T. S.; Dominiak, P. M.; Detty, M. R. “Synthesis, Spectral Data, and Crystal Structure of Two Novel Substitution Patterns in Dithiaporphyrins,” J. Porphyrins Phthalocyanines 2007, 11, 1-8.
5. Wagner, S. J.; Skripchenko, A.; Thompson-Montgomery, D.; Awatefe, H.; Donnelly, D. J.; Detty, M. R. “Use of a Red Cell Band 3-ligand/antioxidant to Improve Red Cell Storage Properties Following Virucidal Phototreatment with Chalcogenoxanthylium Photosensitizers for Pathogen Reduction,” Photochem. Photobiol. 2006, 76, 514-517.
6. Shugart, E. L.; Ahsan, K.; Detty, M. R.; Bright, F. V.* “Site Selectively Templated and Tagged Xerogels for Chemical Sensors,” Anal. Chem. 2006, 78, 3165-3170.
7. Holt, J. J.; Gannon, M. K.; Tombline, G.; McCarty, T. A.; Page, P. M.; Bright, F. V.; Detty, M. R.* “ A Cationic Chalcogenoxanthylium Photosensitizer Effective in Vitro in Chemosensitive and Multidrug-resistant Cells,” Biorg. Med. Chem. 2006, 14, 8635-8643.
8. You, Y.; Gibson, S. L.; Detty, M. R. “Phototoxicity of a Core-Modified Porphyrin and Induction of Apoptosis,” J. Photochem. Photobiol. B 2006, 85, 155-162.
9. Tombline, G.; Donnelly, D. J.; Holt, J. J.; You, Y.; Ye, M.; Gannon, M. K.; Nygren, C. L.; Detty, M. R. “Stimulation of P-glycoprotein ATPase by Analogues of Tetramethylrosamine: Coupling of Drug Binding at the “R” Site to the ATP Hydrolysis Transition State,” Biochemistry 2006, 45, 8034-8047.
10. Goodman, M. A.; Detty, M. R.* “Selenoxides as Catalysts for Epoxidation and Baeyer-Villiger Oxidation with Hydrogen Peroxide,” SYNLETT 2006, 1100-1104.
11. Gibson, S. L.; Holt, J. J.; Ye, M.; Donnelly, D. J.; Ohulchanskyy, T. Y.; You, Y.; Detty, M. R. “Structure-Activity Studies of Uptake and Phototoxicity with Heavy-Chalcogen Analogues of Tetramethylrosamine in Vitro in Chemosensitive and Multidrug-Resistant Cells,” Biorg. Med. Chem. 2005, 13, 6394-6403.
12. You, Y.;* Gibson, S. L.; Detty, M. R. “Core-modified Porphyrins. Part 5. Electronic Effects on Photophysical and Biological Properties in Vitro,” Biorg. Med. Chem. 2005, 13, 5968-5980.
13. Wagner, S. J.; Skripchenko, A.; Donnelly, D. J.; Ramaswamy, K.; Detty, M. R.* “Chalcogenoxanthylium Photosensitizers for the Photodynamic Purging of Blood-Borne Viral and Bacterial Pathogens,” Biorg. Med. Chem. 2005, 13, 5927-5935.
14. Del Valle, D. J.; Donnelly, D. J.; Holt, J. J.; Detty, M. R. “2,7-Bis-N,N-dimethylaminochalcogenoxanthen-9-ones via Electrophilic Cyclization with Phosphorus Oxychloride,” Organometallics 2005, 24, 3807-3810.
15. Tang, Y.; Finlay, J. A.; Kowalke, G. L.; Meyer, A. E.; Bright, F. V.; Callow, M. E.; Callow, J. A.; Wendt, D. E.; Detty, M. R.* “Hybrid Xerogel Films as Novel Coatings for Antifouling and Fouling Release,” Biofouling 2005, 21, 59-71.
16. You, Y.;* Gibson, S. L.; Hilf, R.; Detty, M. R.* “Core-Modified Porphyrins. Part 4. Steric Effects on Photophysical and Biological Properties in Vitro,” Biorg. Med. Chem. 2005, 13, 2235-2251.