- New synthetic methodology
- Asymmetric catalysis
- Natural product synthesis
- Assistant Professor of Chemistry and Medicinal Chemistry (2002)
- NIH Postdoctoral Fellow, Memorial Sloan-Kettering Cancer Center, NY, NY (1999-2002)
- Ph.D., Indiana University (1999)
- B. A., Boston University (1994)
- ACS Administered PRFG (2004-2006)
Research in the Chemler group involves the development and study of new organic and organometallic reactions and the application of these reactions to the synthesis of valuable natural products and designed molecules with interesting molecular architecture and potent biological activity.
The Chemler group has recently discovered novel oxidative cyclization chemistry enabled by relatively inexpensive and non-toxic copper salts. In this context, the generality, mechanism and application of the copper promoted/catalyzed intramolecular carboamination and diamination of unactivated olefins are being explored. The efficiency of these methods in the synthesis of medicinally relevant nitrogen heterocycles is underway.
Selected Recent Publications